The Reaction of Aromatic Amidines with Aromatic Aldehydes

The estimation of aromatic amidines.

Reaction of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol

Reactions of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol in a 1:1:1 molar ratio, afforded 5-(5-aryl-4-benzoyl-3-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-1,3,4-thiadizole-2-thiols (3a-c). The structure of the resulted products was confirmed by determination of the melting point and spectrophotometric techniques such as IR and 1H-NMR spectroscopy.

Reaction of benzoxasilocines with aromatic aldehydes: Synthesis of homopterocarpans

Condensation of 2H-benzo[g][1,2]oxasilocines with aromatic aldehydes in the presence of boron trifluoride affords mixtures of cis/trans 2-phenyl-3-vinylchromans with moderate yields. These can be transformed into homopterocarpans, a synthetic group of substances homologous to the natural isoflavonoid pterocarpans.

Selective Liquid Phase Ammoxidation of Aromatic Aldehydes to Aromatic Nitriles with VPO Titania Heterogeneous Catalysts in Air

 Preparation of 2-Chlorobenzonitrile, and benzonitrile are reported here from the corresponding 2-Chlorobenzaldehyde and benzaldehyde by the reaction of ammonium hydroxide/VPO titania, VPO bulk (...

The determination of aromatic amidines in plasma and urine.

Certain aromatic amidines have been reported to be useful chemotherapeutic agents for the treatment of leishmaniasis, trypanosomiasis, and babesiasis (1). Pharmacological and clinical studies of these compounds have been handicapped by lack of suitable methods for the determination of aromatic amidines in plasma and urine. Recently Fuller (2) described a method which is based upon a reaction be...